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Oestrogen Cream

Natural Menopause Relief

Bioidentical oestrogen cream for the relief of chronic menopause symptoms in women deficient in oestrogen *

Oestrogen Cream

Natural Menopause Relief

Bioidentical oestrogen cream for the relief of chronic menopause symptoms in women deficient in oestrogen

Natural Oestrogen Cream

For over 25 years Wellsprings creams have been chosen by women and doctors as a natural alternative to Hormone Replacement Therapy (HRT).

Many women who use them report that their menopause symptoms are relieved and quality of life improved, without the side-effects often experienced with common HRT treatments. *
Effective Symptom Relief
Including hot flushes, night sweats, low libido, vaginal dryness, brain fog, mood problems, insomnia and headaches.*
Natural, Bioidentical Hormones
The active ingredient in Wellsprings Oestrogen Cream is natural oestrogen which is bioidentical to your body’s own oestrogen. *
Tried and Tested
Wellsprings bioidentical hormone creams have been helping relieve the symptoms of menopause for thousands of women since 1997. *

Vaginal Symptoms

As well as bringing relief from many common menopause symptoms such as hot flushes and night sweats, bioidentical oestrogen cream is particularly helpful for women suffering from vaginal issues caused by the menopause.

See here for our standard usage instructions, but note that Wellsprings Oestrogen Cream can also be applied vaginally if required.

The dramatic reduction in oestrogen levels at menopause can cause a decrease in natural lubrication, resulting in dryness and other vaginal issues.

Many women find relief by using lubricants or vaginal moisturisers, but applying Wellsprings Oestrogen Cream vaginally can provide deeper and longer term relief from dryness.

Another common side effect of menopause is dyspareunia, or painful intercourse, resulting from vaginal dryness and thinning of the vaginal tissues.

For some women, this causes a general sense of discomfort during intercourse while others experience severe pain as well as soreness and burning.

Vaginal atrophy is another serious problem which can affect up to 50% of menopausal women and which can also be eased by the application of oestrogen cream.

Bioidentical Oestrogen

Wellsprings Oestrogen Cream replenishes your body with oestrogen that is bioidentical to that produced in the body naturally, restoring hormone balance and relieving the symptoms of menopause.

Why a Cream?

In pill form bioidentical hormones are filtered out by the liver, so we use a hyper-liposomal cream which optimises oestrogen absorption and maximises symptom relief.
What doctors say about Wellsprings' hormone creams...
Dame Dr Shirley Bond
"I had never been keen to give my patients traditional HRT and now I had a safe product to use to help them deal with their problems and balance their hormones."
Dr B Peatfield
"I have been using natural progesterone cream for some years now... both my patients and I have, without exception, been delighted with its efficacy."

What our customers say about our natural hormone creams...
Christine, Cambs
"The flushes have reduced... My weight is slowly coming back down... I can’t recommend this product enough, Thank you Serenity." *
Jane, Surrey
"My anxiety and hot flushes have gone. I lost 7 pounds in weight in 10 days. I’m high on life and feel and look wonderful." *
GB, Doncaster
"I have been using Serenity cream for three months... I feel healthy and energetic and symptoms are less severe each month." *

* Please note that our customer reviews are individual experiences. Your results may vary.


A Premium Oestrogen Cream

Wellsprings Oestrogen Cream is a gentle, fragrance free, natural oestrogen cream with an advanced liposomal formula that optimises absorption.

Certified Bioidentical Oestrogen Content

1% Natural Estriol
Each 100ml (3.5oz) jar of Wellsprings Oestrogen Cream contains 1,000mg of bioidentical USP pharmaceutical grade bioidentical oestrogen extracted from plant saponins.

Advanced Liposomal Formula

Enhanced Absorption
Our advanced liposomal formula optimises oestrogen absorption while keeping skin looking healthy and moisturised in areas where applied.


All natural ingredients
Free from common allergens.

Fragrance Free

For discreet application
Wellsprings Oestrogen Cream is fragrance free so as not to interfere with other scented products you may be using.

Animal Friendly

No animal testing
Our creams are not tested on animals in any way and no animal by-products are used in their formulation.


Deionized Water, Aloe Barbadensis Leaf Juice, Organic Glycine Soja (Soybean) Oil, Glycerin, Glyceryl Stearate SE, Isopropyl Myristate, Cetyl Alcohol, Methyl Glucose Sesquistearate, Stearic Acid, Phenoxyethanol, Caprylyl Glycol, Sodium PCA, Estriol (1%), Tocopheryl Acetate, Carbomer, PEG-20 Methyl Glucose Sesquistearate, Citrus Grandis (Grapefruit) Seed Extract, Xanthan Gum, Aminomethyl Propanol, Sorbic Acid, Sodium Hyaluronate.
Manufactured in the USA
A dose of Wellsprings Oestrogen Cream cream should be applied morning and bedtime vaginally (if required) and to thin tissue areas of the body, avoiding the breast area. It is important to massage the cream into a different area each time.

Each recommended dose of cream is 1/8th of a teaspoon (0.5ml). This amount is the size of a garden pea.

We recommend using a double dosage (2 pea-sized amounts of cream, twice a day) for the first month of application. Also, please ensure you finish the full pump bottle of your cream to allow time for your hormone levels to stabilise and symptoms to be properly treated.

To dispense a pea-sized amount from the pump bottle, gently press the pump until the correct amount is dispensed.*

Usage Schedule *
Usage Schedule *
* Typical usage for best performance. Your results may vary.

Usage Variations

If symptoms are severe you may use a double dose mornings and evenings, but all women are different and dosage should be assessed and modified by each individual through their own experience over a period of time.

Apply the cream directly to the vagina for the relief of menopause-related vaginal dryness, vaginal atrophy and painful intercourse.

Wellsprings Oestrogen Cream can be used alone or in conjunction with Wellsprings Serenity progesterone cream or Wellsprings 20-1 progesterone and oestrogen combination cream, to deliver an additional amount of oestrogen into your dosing regime if required.

Each 100ml pump bottle contains around 200 pea-sized doses, so a pump bottle will last approximately four months with average usage.*


Applying Cream

Wellsprings Oestrogen Cream should be applied to thin tissue areas of the body, rotating between different areas each day.

The best application areas are: the face, neck, inside of the upper arms, lower back and inner thighs.

Top Tip

Top Tips
How to measure a single dose
Simply dab the underside of your little finger halfway to the nail if using a jar, or gently press the pump if using our pump bottle. The amount should be about the size of a garden pea.

Top Tip

Quick Relief
For a more instant effect (for migraine headaches for example) it has been found that massaging a little extra cream into the areas of thin skin (inner wrists, temples and behind the ears) may give relief.
* Every woman is unique. Your results may vary
Hormonal changes during menopause may encourage weight gain.
Hear what doctors have to say about natural progesterone and its benefits
Discover the natural alternative to hormone replacement therapy
Natural progesterone can be an effective treatment for this serious condition
What happens to hormones at menopause and how can symptoms be treated?
Understand what's behind the increased incidence of oestrogen dominance in the western world
Learn about the condition behind menopause symptoms
How can a cream deliver progesterone into the body?
What are bioidentical hormones and why are the relevant to your health
How do progesterone creams work and where did they come from
Wellsprings offers two varieties of natural progesterone cream. Read on to find out which is best for you
Oestrogen dominance can interfere with thyroid hormone activity
Despite claims to the contrary, Yam Extract does NOT contain progesterone or raise progesterone levels in the body

All information given on this site is for general interest only. Every woman is unique. Your results may vary.
Serenity Cream Questions
of Wellsprings creams
* Please note that our customer reviews are individual experiences. Your results may vary.