Getting the most from your Wellsprings bioidentical hormone creams requires understanding proper application techniques, timing, and usage guidelines. This comprehensive guide covers all of our cream products: Serenity, Twenty to One, Oestrogen Cream, Face Serum, and Lifelong Care Cream.

Our Product Range

Wellsprings offers five premium bioidentical hormone products, each designed for specific needs:

  • Serenity Cream - Natural progesterone for menopause and PMS relief
  • Twenty to One (20-1) Cream - Progesterone and oestrogen combination for enhanced menopause symptom relief
  • Oestrogen Cream - Bioidentical estriol for chronic menopause symptoms and vaginal health
  • Lifelong Care Cream - Progesterone, oestrogen, and essential nutrients for long-term post-menopausal health
  • Face Serum - Progesterone and oestrogen formulated specifically for facial skin health

Universal Application Principles

The following guidelines apply to all body creams: Serenity, Twenty to One, Oestrogen Cream, and Lifelong Care Cream.

How Much to Use

The standard dosage for most Wellsprings creams is approximately 1/8th of a teaspoon (0.5ml) applied twice daily - once in the morning and once in the evening. This should be about the size of a garden pea.

How to Measure

If using a jar, simply dab the underside of your little finger halfway to the nail to measure the correct amount. If using our pump bottle, gently press the pump until the required amount of cream is dispensed.

Where to Apply

Bioidentical hormone creams should be applied to thin tissue areas of the body where absorption is optimal. Apply to clean, dry skin in any of these areas:

  • Inside of the upper arms
  • Inside of the lower arms
  • Inner thighs
  • Sides of the abdomen
  • Lower back
  • Behind the knees (occasionally)

Important: Avoid applying cream to the face, neck, and breast area. Always rotate between different areas each day to prevent saturation of hormone receptors in any one location.

How to Apply

Apply the cream to clean, dry skin and gently massage until fully absorbed. Rotating application areas daily is essential for maintaining optimal hormone receptor sensitivity.

Recommended Daily Rotation Routine

Our usage information is based on the recommendations of experienced bioidentical doctors and focuses on rotating the application areas.

This avoids overusing any one receptor site, which can lead to less hormone being absorbed to deal with your symptoms. It focuses on thin tissue areas to give faster absorption and twice daily application for your specific required regime of either 2 or 3 weeks application and gives 24 hour coverage.

A convenient, easy to apply and to remember routine is:

Day Morning Evening
Day 1 L inner thigh R inner thigh
Day 2 L half of abdomen R half of abdomen
Day 3 L inner forearm R inner forearm
Day 4 L inner upper arm R inner upper arm

You then continue this 4-day rotation until your month's cycle of two or three weeks application is completed as recommended for your situation.

Application Timing and Cycles by Hormonal Stage

The following cycling guidance applies to Serenity, Twenty to One, and Oestrogen Cream (when used as a body cream). Lifelong Care Cream has a single, simple cycle for all users - see Product-Specific Guidance below.

The timing of your cream application depends on your hormonal stage:

Pre-Menopause (still having regular periods):

Counting day one of your period as the start of the four week cycle, take a two week break then apply cream twice daily during weeks 3 and 4 of your cycle. Repeat this 4 week cycle. This mimics your body's natural progesterone production pattern.

Peri-Menopause (having irregular periods):

Follow the post-menopause guidance below, but if a bleed occurs at any point within the three week application period, pause the cream for 1 week and then start a completely new 3 week period of application.

Menopausal, Post-Menopause or Post-Hysterectomy (no longer having periods):

Apply cream twice daily for 3 weeks, then pause application for 1 week. Repeat this 4 week cycle consistently.

Why Breaks Are Essential

The one week break each month is crucial for maintaining the sensitivity and optimal absorption of your hormone receptors. Without these breaks, your body may become less responsive to the hormones over time, reducing the cream's effectiveness.

Product-Specific Guidance

Serenity Cream (Progesterone)

Serenity follows all the universal principles outlined above. Each pump bottle lasts 4+ months with regular use. For fast relief from acute symptoms like headaches, you can also massage a little extra cream into the inner wrists, temples, or behind the ears.

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Twenty to One Cream (Progesterone + Oestrogen)

Twenty to One cream is used exactly like Serenity cream, following the same application areas, timing, and cycling. It's designed for women who need additional oestrogen alongside progesterone for more comprehensive symptom relief. Each pump bottle lasts 4+ months.

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Oestrogen Cream

Oestrogen Cream has three different usage scenarios:

Scenario 1: As Additional Oestrogen (with Serenity or 20-1)

If you're already using Wellsprings Serenity or Twenty to One and your symptoms aren't fully controlled, add one pea-sized 0.5ml dose of Oestrogen Cream in the morning alongside your progesterone cream. Apply to the same body area, following the same rotation regime. Each dose contains 1.7mg of estriol. When used as an addition, a bottle may last up to a year.

Scenario 2: For Vaginal Dryness or Atrophy

Apply one pea-sized 0.5ml dose once nightly before bed, intra-vaginally. Use for 2 weeks or until symptoms are controlled, then gradually reduce to 2-3 times per week at the minimum dose that maintains symptom control. If post-hysterectomy, use as for Scenario 1 above - we recommend adding progesterone to protect tissues other than the womb, such as the breasts.

Scenario 3: Oestrogen-Only Regime

While we generally recommend adding a bioidentical progesterone cream like Serenity or Twenty to One to any oestrogen-only regime, if you wish to use oestrogen alone, apply one pea-sized 0.5ml dose morning and evening to thin tissue areas (abdomen, lower thighs, upper inner arms), avoiding the face, neck and breast area. Lightly stroke the cream into a different area each time. Use a 4-week cycle: 3 weeks usage, 1 week off. Each 100ml pump bottle lasts approximately 4 months with full-dose usage.

Important Note: Women with a history or risk of hormonal cancers (personal or family) should consult a healthcare professional before taking any supplemental hormones.

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Lifelong Care Cream (Long-term Health)

Lifelong Care Cream is designed specifically for post-menopausal women and is optimally dosed for long-term use beyond menopause. It contains progesterone, oestrogen, and essential nutrients (magnesium, zinc, and vitamin D) for bone health, immune function, and metabolic wellness.

Apply one pump of cream in the morning and one at bedtime to thin tissue areas (abdomen, inner thighs, upper inner arms), avoiding the breast area. Lightly stroke the cream into a different area each time.

Lifelong Care has a single, simple cycle for all users: Apply cream twice daily for 3 weeks, then take 1 week off. Repeat this 4-week cycle. The one week break is essential to maintain receptor sensitivity.

Each bottle lasts 4+ months. If you're new to Lifelong Care, a double dose can be used for the first month to quickly restore healthy hormone levels.

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Face Serum (Facial Application Only)

Face Serum is completely different from our body creams and is formulated specifically for facial skin health. Use twice daily (morning and evening) as part of your facial skincare routine. Cleanse skin thoroughly, then apply a pea-sized amount using small tapping or pressing motions with your fingertips. Do not rub - let the serum absorb on its own. For best results, apply to slightly damp skin. Face Serum requires no breaks and can be used continuously, even after menopause. It can be used alongside any of our body creams without changing dosage. Each 50ml pump bottle lasts 6+ weeks.

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Getting Started with Wellsprings Creams

If you're new to Wellsprings creams, we recommend using a double dosage (two pea-sized amounts of cream, twice daily) for the first month of application, or until symptoms improve. This helps to quickly restore healthy hormone levels. Please ensure you finish the full jar or pump bottle to allow time for your hormone levels to stabilise and symptoms to be properly treated.

Combining Products

You can combine Wellsprings products for enhanced results:

  • Add Oestrogen Cream to Serenity or Twenty to One if symptoms aren't fully controlled
  • Use Face Serum alongside any body cream without adjusting dosage
  • All body creams follow the same application areas and rotation principles

Storage and Shelf Life

Store all creams in a cool, dry place away from direct sunlight. Check expiration dates and replace as needed to ensure potency.

Monitoring Your Progress

Keep track of your symptoms and how you feel throughout your cycles. It may take 2-3 months to see the full benefits as your hormone levels stabilise. As with any supplementation, it's important to monitor your symptoms - dosage can be varied as required. If you have concerns or questions about your progress, consult with a healthcare professional familiar with bioidentical hormone therapy.

Tips for Success

  • Consistency is key - apply at approximately the same times each morning and evening
  • Always apply to clean, dry skin
  • Rotate application areas daily
  • Don't skip the weekly breaks (essential for receptor sensitivity)
  • Finish your first bottle to allow proper hormone stabilisation
  • Track your symptoms to monitor progress
  • Store properly to maintain potency

Following these guidelines will help ensure you get the maximum benefit from your Wellsprings creams while maintaining your body's natural hormone balance. Remember, every woman is unique - your results may vary, but proper usage is the foundation for optimal effectiveness.
* This information is for general interest only. Every woman is unique. Your results may vary.